Government agencies will introduce approaches to ISS Transition and low Earth orbit (LEO) commercialization, highlighting utilization activities designed to build sustainable demand for LEO services. Speakers will discuss activities and plans for operations, research, and development in LEO, including capabilities the ISS currently provides, as well as plans for developing a commercial space industry and commercial space marketplace. They discuss how they envision the LEO landscape of the 2020s and beyond and key issues that must be considered when contemplating a transition from the ISS to other platforms.